Let us see an example. A person is walking in the park. He sees something like a snake and thinks in his mind "It is a snake." That message of fear goes to other parts of the brain, then to the spinal cord, and then to the rest of the body. In a very short period, the whole body knows about the danger and prepares itself to face the danger. The heart rate increases, blood pressure increases, breathing becomes faster. Blood is diverted from the brain to the muscles, the hands and the feet. As a result, the person is ready to "fight" or "to run away". This well known phenomenon is called "fight-or-flight" response. Just the thought "snake" creates this response.
In the same way, there is a biological basis for every thought.